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siroheme biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
S-adenosyl-L-methionine + uroporphyrinogen_III <=> H+ + S-adenosyl-L-homocysteine + precorrin-1 2.1.1.107 uroporphyrinogen-III C-methyltransferase

sirohydrochlorin + Fe2+ <=> H+ + siroheme 4.99.1.3 sirohydrochlorin cobaltochelatase
4.99.1.4 sirohydrochlorin ferrochelatase


S-adenosyl-L-methionine + precorrin-1 <=> S-adenosyl-L-homocysteine + precorrin-2 2.1.1.107 uroporphyrinogen-III C-methyltransferase

precorrin-2 + NAD+ <=> H+ + sirohydrochlorin + NADH 1.3.1.76 precorrin-2 dehydrogenase

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